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TRUST-AI.

Remi Rothwell1, Adam Julius1, Robert Crichton1

  • 1University College London, London, UK.

Journal of Perioperative Practice
|December 1, 2025
PubMed
Summary
This summary is machine-generated.

We propose TRUST-AI, a new guide for healthcare professionals to evaluate artificial intelligence (AI) systems. This framework ensures responsible AI adoption by addressing key domains for safe and effective integration into healthcare.

Keywords:
Artificial intelligenceDigital literacyFrameworkGuideline

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Area of Science:

  • Healthcare Technology
  • Medical Informatics
  • Artificial Intelligence in Medicine

Background:

  • Artificial intelligence (AI) offers significant potential to improve healthcare decision-making, efficiency, and patient outcomes.
  • Widespread adoption of AI in healthcare is hindered by persistent concerns and limitations of current reporting guidelines.
  • Existing guidelines struggle to adapt to the rapid evolution of novel AI technologies.

Purpose of the Study:

  • To introduce TRUST-AI, a high-level evaluation guide for artificial intelligence systems in healthcare.
  • To provide healthcare professionals with a framework for the responsible assessment of AI technologies.
  • To ensure the enduring relevance of AI evaluation principles amidst technological advancements.

Main Methods:

  • Development of a novel, high-level guide named TRUST-AI.
  • Distillation of seven core domains for AI evaluation: Transparency, Reliability, Use Case, Safety and Security, Treatment Equity, Affordability and Environmental Impact, and Integration.
  • Design of the guide by and for healthcare professionals to ensure practical applicability.

Main Results:

  • The TRUST-AI guide offers a structured approach to evaluating AI systems in healthcare.
  • It addresses critical aspects beyond technical performance, including ethical and practical considerations.
  • The framework is designed for adaptability to diverse and evolving AI technologies.

Conclusions:

  • TRUST-AI empowers healthcare professionals to act as informed gatekeepers for AI implementation.
  • The guide facilitates the establishment of trust in artificial intelligence within the healthcare sector.
  • Responsible evaluation through TRUST-AI promotes the safe and equitable integration of AI into evolving health systems.