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Updated: Jan 9, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma

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Published on: April 12, 2024

EndoCompass Project: Research Roadmap for Growth Disorders.

Evelien F Gevers^1,2, Anita C Hokken-Koelega³, Maithe Tauber⁴

¹Centre for Endocrinology, William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, UK, evelien.gevers@nhs.net.

Hormone Research in Paediatrics

|December 1, 2025

Summary

This summary is machine-generated.

Endocrinology research funding in the EU needs strategic prioritization. The EndoCompass project identified key growth disorder research areas to improve hormone health and reduce disease burden.

Keywords:

Growth hormone Imprinting disorders Noonan syndrome Prader-Willi syndrome Short stature Silver-Russell syndrome Tall stature

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Area of Science:

Endocrinology and hormone health research
Pediatric endocrinology and growth disorders

Background:

Endocrine science is underrepresented in EU research programs, despite the importance of hormone health.
A gap exists between the societal impact of endocrine disorders and their research prioritization.
The EndoCompass project aims to define strategic research priorities in endocrine science.

Purpose of the Study:

To identify and promote strategic research priorities in endocrine science.
To address critical hormone-related health challenges.
To align research funding with areas of highest potential impact.

Main Methods:

Analysis of the EU CORDIS database (Horizon 2020).
Expert consultations on growth disorders.
Stakeholder engagement with society members and patient advocacy groups.

Main Results:

Priorities include genetic diagnosis, growth plate therapies, and molecular mechanisms of specific syndromes (Silver-Russell, imprinting, Prader-Willi, Noonan).
Focus on disease registries for outcome studies.
Development of precision therapeutics based on growth regulation pathways.

Conclusions:

An evidence-based roadmap for strategic research investment in endocrine growth disorders.
Identifies key areas for pathophysiology, prevention, and treatment.
Aims to reduce the burden of growth disorders on individuals and society.