Reflective functioning in anorexia nervosa: does it differ from healthy controls and what is its relation to
Lara Maria Kanstinger1, Almut Zeeck1, Armin Hartmann1
1Department of Psychosomatic Medicine und Psychotherapy, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Journal of Eating Disorders
|December 2, 2025
Summary
Patients with anorexia nervosa (AN) exhibit impaired mentalizing abilities, as confirmed by expert ratings and self-reports. Strengthening mentalization may be a key treatment focus for AN.
Area of Science:
- Psychiatry
- Psychology
- Clinical Psychology
Background:
- Previous research indicates reduced mentalizing capacity, or reflective functioning (RF), in anorexia nervosa (AN) patients.
- Few studies have utilized validated interview procedures to assess RF in AN.
- This study aimed to evaluate RF in AN patients compared to healthy controls (HCs) using expert-rated and self-report measures.
Purpose of the Study:
- To assess and compare reflective functioning (RF) in female patients with anorexia nervosa (AN) and healthy controls (HCs).
- To explore the relationship between RF and various psychopathological aspects in AN.
- To compare expert-rated and self-report measures of RF in AN.
Main Methods:
- 30 female AN patients and 30 matched HCs were assessed.
- Reflective functioning (RF) was measured using the Brief Reflective Functioning Interview (BRFI) and the Mentalization Questionnaire (MZQ).
- Correlations were examined between RF and eating disorder psychopathology, body experience, general psychopathology, and personality functioning.
Main Results:
- AN patients showed significantly lower RF on the expert-rated RF-Scale (RF-BRFI) compared to HCs (p=0.011).
- Self-reported mentalizing (MZQ) was also significantly worse in the AN group compared to HCs (p<0.0001).
- RF measured by BRFI correlated only with 'weight concern', while MZQ RF correlated with various psychopathology aspects, excluding depressive symptoms and BMI.
Conclusions:
- The study confirms impaired mentalizing in AN patients.
- Enhancing mentalization abilities could be a significant therapeutic target for AN.
- The association between RF and psychopathology is dependent on the specific RF measurement tool used, necessitating further research into their distinct captured aspects.
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