Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthetic Biology02:55

Synthetic Biology

5.5K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.5K
The Central Dogma01:20

The Central Dogma

31.6K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
31.6K
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

536
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
536

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predicting Bacterial Radiation Resistance Through Identifying Novel Genomic Features.

Environmental microbiology·2026
Same author

Deep Learning-Enhanced Generation and Screening of Antihyperuricemic Peptides from Chickpea Proteins: from Multienzyme Optimization to Molecular Mechanisms.

Journal of agricultural and food chemistry·2026
Same author

A Magnetic Bimodal Mesoporous Silica Biocatalyst via Cellulase Immobilization for Sustainable Production of Chitosan Oligosaccharides.

Journal of agricultural and food chemistry·2026
Same author

Advances in Microbial and Enzymatic Degradation of Deoxynivalenol (DON).

Journal of agricultural and food chemistry·2026
Same author

Combining Signal Peptide Optimization with Directed Evolution to Enhance Chitosanase Activity.

Journal of agricultural and food chemistry·2025
Same author

Enhancing Chitosanase Activity via Directed Evolution and Its Molecular Mechanisms.

Journal of agricultural and food chemistry·2025

Related Experiment Video

Updated: Jan 9, 2026

Rapid, Enzymatic Methods for Amplification of Minimal, Linear Templates for Protein Prototyping using Cell-Free Systems
07:35

Rapid, Enzymatic Methods for Amplification of Minimal, Linear Templates for Protein Prototyping using Cell-Free Systems

Published on: June 14, 2021

3.1K

Trends in Customizable Single-Cell Protein Production Enabled by Synthetic Biology: Carbon-Negative Biomanufacturing

Zhihan Yang1, Lin Li1, Yingli Chen1

  • 1College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China.

Journal of Agricultural and Food Chemistry
|December 2, 2025
PubMed
Summary

Synthetic biology advances single-cell protein (SCP) production by optimizing feedstocks, microbial strains, and fermentation. This positions SCP as a sustainable protein source for animal feed and future human foods.

Keywords:
nutritional customizationprecision fermentationsingle-cell proteinsynthetic biologythird-generation feedstocks

More Related Videos

Escherichia coli-Based Cell-Free Protein Synthesis: Protocols for a robust, flexible, and accessible platform technology
09:45

Escherichia coli-Based Cell-Free Protein Synthesis: Protocols for a robust, flexible, and accessible platform technology

Published on: February 25, 2019

37.2K
Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

9.5K

Related Experiment Videos

Last Updated: Jan 9, 2026

Rapid, Enzymatic Methods for Amplification of Minimal, Linear Templates for Protein Prototyping using Cell-Free Systems
07:35

Rapid, Enzymatic Methods for Amplification of Minimal, Linear Templates for Protein Prototyping using Cell-Free Systems

Published on: June 14, 2021

3.1K
Escherichia coli-Based Cell-Free Protein Synthesis: Protocols for a robust, flexible, and accessible platform technology
09:45

Escherichia coli-Based Cell-Free Protein Synthesis: Protocols for a robust, flexible, and accessible platform technology

Published on: February 25, 2019

37.2K
Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

9.5K

Area of Science:

  • Biotechnology
  • Synthetic Biology
  • Sustainable Food Production

Background:

  • Growing global population necessitates sustainable protein alternatives beyond conventional agriculture.
  • Single-cell protein (SCP) shows promise but faces challenges in feedstock, efficiency, and scalability.

Purpose of the Study:

  • To review how synthetic biology innovations address barriers in the SCP value chain.
  • To explore SCP's potential for both animal feed and human food applications.

Main Methods:

  • Examining substrate evolution from sugars to C1 compounds and waste streams.
  • Analyzing advancements in microbial strain engineering and metabolic pathway optimization.
  • Investigating precision fermentation control and digital integration.

Main Results:

  • Engineered microbes demonstrate enhanced C1 assimilation capabilities.
  • Metabolic engineering and rational design improve protein biosynthesis efficiency.
  • Digitalized, model-based fermentation enables robust, scalable bioprocessing.

Conclusions:

  • Synthetic biology offers solutions to SCP production challenges across the value chain.
  • SCP can be nutritionally customized for diverse human food applications, enhancing sensory acceptance.
  • SCP represents a versatile and sustainable protein source for future food systems.