Recent trends in mesoporous carbon-based nanoplatforms for biomedical application

Area of Science:

• Nanotechnology and Materials Science
• Biomedical Engineering
• Drug Delivery Systems

Background:

• Mesoporous carbon nanoparticles (MCNs) possess unique structural features like high surface area and tunable pore sizes.
• These properties address limitations in conventional drug delivery, such as inefficient loading and release, and minimize side effects.
• MCNs exhibit remarkable biocompatibility, making them promising for various biomedical applications.

Purpose of the Study:

• To review the classification and research progress of MCNs.
• To summarize preparation, modification, and physicochemical properties of MCNs.
• To highlight MCNs' applications in tumor therapy, theranostics, antibacterial uses, active molecule delivery, and biological detection.

Main Methods:

• Literature review of MCNs' classification, preparation, modification, and properties.
• Analysis of MCNs' performance in diverse biomedical applications.
• Examination of MCNs' potential for clinical translation.

Main Results:

• MCNs demonstrate significant potential in enhancing drug loading and release efficiencies.
• Their application spectrum includes advanced tumor therapy, theranostics, and antibacterial strategies.
• MCNs are effective in delivering active molecules and in biological detection systems.

Conclusions:

• MCNs are versatile nanomaterials with significant advantages for biomedical applications.
• Further research and development are crucial for overcoming challenges in clinical translation.
• MCNs hold promise for revolutionizing future therapeutic and diagnostic strategies.