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Updated: Jan 9, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

Weighted Non-linear Beamformer for PLD-based Photoacoustic Imaging Systems: Initial Results.

Anwar Tesfaye Beshir, Arun Kumar Thittai

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|December 3, 2025

Summary

A new Filtered Delayed Euclidean-weighted Multiply and Sum (F-DewMAS) beamformer significantly improves photoacoustic imaging quality. This advanced method enhances resolution and contrast, offering a better alternative for pulsed laser diode systems.

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Published on: May 30, 2019

Area of Science:

Biomedical Optics
Acoustic Imaging
Signal Processing

Background:

Photoacoustic imaging (PAI) offers unique capabilities for visualizing biological tissues.
Conventional beamforming methods like Delay and Sum (DAS) and Filtered Delay Multiply and Sum (F-DMAS) have limitations in image quality.
Pulsed laser diode (PLD)-based PAI systems require advanced techniques for optimal performance.

Purpose of the Study:

Introduce and evaluate a novel nonlinear beamforming method, Filtered Delayed Euclidean-weighted Multiply and Sum (F-DewMAS).
Compare the performance of F-DewMAS against DAS and F-DMAS in terms of key image quality metrics.
Assess the potential of F-DewMAS for enhancing PLD-based PAI systems.

Main Methods:

Developed the F-DewMAS beamforming algorithm.
Conducted simulations using point sources arranged in an 'IITM' pattern.
Performed phantom experiments with graphite absorbers.
Quantitatively analyzed Axial Resolution (AR), Lateral Resolution (LR), Contrast Ratio (CR), Contrast to Noise Ratio (CNR), and Signal to Noise Ratio (SNR).

Main Results:

F-DewMAS demonstrated superior performance over DAS and F-DMAS in both simulations and phantom experiments.
Achieved up to 24% improvement in CR, 28% in CNR, and 31% in SNR compared to DAS.
Showcased significant improvements in AR (33% over DAS) and LR (38% over DAS).
Average AR of 0.356 mm and LR of 1.194 mm were achieved with F-DewMAS.

Conclusions:

F-DewMAS is a highly effective nonlinear beamforming technique for photoacoustic imaging.
The method offers substantial improvements in image resolution and quality, particularly for PLD-based systems.
F-DewMAS presents a promising and practical alternative to existing beamforming approaches for advanced diagnostics.