Physical Activity Interventions for Patients With Poststroke Fatigue: Protocol for a Scoping Review

Area of Science:

• Neurology
• Rehabilitation Medicine
• Evidence Synthesis

Background:

• Poststroke fatigue (PSF) impacts nearly 50% of stroke survivors, hindering recovery and quality of life.
• Physical activity (PA) interventions show potential for mitigating PSF, but evidence is fragmented.

Purpose of the Study:

• To systematically map existing literature on PA interventions for PSF.
• To identify key concepts, evidence gaps, and implementation characteristics.
• To guide future research and clinical practice for PSF management.

Main Methods:

• A 5-step scoping review framework will be employed.
• Searches will cover major databases (PubMed, Web of Science, etc.) and gray literature.
• Two reviewers will independently screen and extract data on interventions, fatigue assessment, and outcomes.

Main Results:

• Initial searches yielded 8268 articles.
• Study selection is anticipated to conclude in February 2026.
• Manuscript submission is planned for June 2026.

Conclusions:

• This review will synthesize a fragmented evidence base on PA for PSF.
• Findings will highlight research gaps and inform definitive studies and clinical guidelines.
• The ultimate goal is to improve care for stroke survivors experiencing fatigue.