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Data Augmentation for Few-Shot Biomedical NER Using ChatGPT.

Wenxuan Mu1, Di Zhao1, Jiana Meng1

  • 1Dalian Minzu University, Dalian, 116650, China.

Artificial Intelligence in Medicine
|December 3, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a new data augmentation method for biomedical Named Entity Recognition (NER) using ChatGPT and prompt learning. The approach enhances model performance in low-data scenarios, achieving high accuracy in few-shot settings.

Keywords:
Biomedical named entity recognitionChatGPTData augmentationFew-shot learningNatural language processingPrompt learningSeparable convolutionsTransfer learning

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Area of Science:

  • Biomedical Natural Language Processing
  • Machine Learning

Background:

  • Data scarcity is a significant challenge in biomedical Named Entity Recognition (NER).
  • Few-shot learning scenarios require effective data augmentation (DA) to improve model generalization and reduce overfitting.
  • Existing DA methods may not adequately address the complexities of biomedical text.

Purpose of the Study:

  • To propose a novel DA method for biomedical NER tasks.
  • To leverage large language models (LLMs) like ChatGPT for high-quality data generation.
  • To enhance the performance of NER models in low-data and few-shot settings.

Main Methods:

  • Utilized ChatGPT and prompt learning to extract high-quality data for NER.
  • Employed transfer learning and efficient decoding strategies for entity recognition.
  • Conducted experiments on four public biomedical datasets: BC5CDR, NCBI, BioNLP11EPI, and BioNLP13GE.

Main Results:

  • The proposed DA method demonstrated strong stability and entity recognition capabilities in extremely limited data scenarios.
  • Achieved average F1 scores of 72.96% (5-shot), 75.05% (20-shot), and 77.42% (50-shot) across the four datasets.
  • Showcased significant improvements in model generalization ability in few-shot NER tasks.

Conclusions:

  • The novel DA method effectively addresses data scarcity in biomedical NER.
  • ChatGPT and prompt learning offer a powerful approach for generating high-quality training data.
  • The method shows promise for improving NER model performance in challenging, low-resource biomedical domains.