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Updated: Jan 9, 2026

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Published on: April 4, 2025
Challenging laparoscopic radical nephrectomy in pregnancy.
Matthew Kwon1, Ahmad Alam2, Eugene Mansour3
1Urology, Hunter New England Local Health District, New Lambton, New South Wales, Australia mkwon98@hotmail.com.
Managing renal cell carcinoma (RCC) in pregnancy requires balancing cancer treatment with fetal safety. Laparoscopic nephrectomy during the second trimester proved successful for a large clear cell RCC, ensuring good outcomes for mother and baby.
Area of Science:
- Oncology
- Obstetrics
- Surgical Innovation
Background:
- Renal cell carcinoma (RCC) during pregnancy is exceptionally rare.
- It poses significant challenges in balancing maternal cancer treatment with fetal well-being.
- Clinical decisions require careful consideration of oncological urgency versus obstetric risks.
Purpose of the Study:
- To present a successful management strategy for a pregnant patient with clear cell renal cell carcinoma.
- To highlight the feasibility and safety of surgical intervention during pregnancy.
- To emphasize the importance of a multidisciplinary approach in complex cases.
Main Methods:
- Case report of a pregnant patient with an incidentally detected large clear cell RCC.
- Surgical management involved laparoscopic radical nephrectomy.
- Intervention was performed during the second trimester of pregnancy.
Main Results:
- Successful surgical removal of the renal cell carcinoma.
- Favorable oncological and fetal outcomes were achieved.
- The patient and fetus tolerated the procedure well.
Conclusions:
- Laparoscopic radical nephrectomy is a viable and safe option for managing renal cell carcinoma in pregnant patients.
- Multidisciplinary collaboration is crucial for optimizing outcomes.
- Tailored surgical planning is essential for achieving success in these unique cases.
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