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Design Innovation for Engaging and Accessible Digital Aphasia Therapies: Framework Analysis of the iReadMore App
Tom Langford1, Victoria Fleming1,2, Emily Upton1
1UCL Queen Square Institute of Neurology University College London London United Kingdom.
JMIR Neurotechnology
|December 4, 2025
Summary
This study presents a co-design methodology for the iReadMore digital therapy app, enhancing accessibility and engagement for individuals with acquired reading impairments (alexia) and poststroke aphasia. The redesigned app is now publicly available for rehabilitation.
Area of Science:
- Neuroscience
- Digital Health
- Human-Computer Interaction
Background:
- iReadMore is a digital therapy for alexia caused by brain injury or neurodegeneration.
- A Phase II trial showed prototype efficacy for poststroke aphasia and alexia but highlighted challenges in home-based self-management.
- Subsequent design innovation was needed to translate research findings into real-world benefits.
Purpose of the Study:
- To present a methodology for inclusive co-design in redesigning a digital therapy prototype.
- To focus on enhancing accessibility and user engagement in digital therapies for aphasia.
- To explore themes from co-design communications and interactions using framework analysis.
Main Methods:
- A two-stage study involving in-person and remote co-design sessions with participants experiencing poststroke aphasia and their carers.
- Data collection via video recordings, participant notes, and drawings from co-design sessions.
- Qualitative framework analysis to identify themes relevant to digital aphasia therapy design.
Main Results:
- Seven key areas for digital aphasia therapy design were identified: agency, intuitive design, motivation, personal trajectory, relatable content, social/sharing aspects, and widening participation.
- The co-design process facilitated the deployment of the iReadMore app in an accessible and engaging format.
- Framework analysis provided insights into crucial design considerations for digital therapies targeting individuals with aphasia.
Conclusions:
- Co-design is vital for innovating digital therapies, leveraging technology for user-centered design.
- The co-designed iReadMore app is now available for rehabilitation of acquired reading impairments.
- This paper offers a methodology for inclusive co-design with people with aphasia and highlights key design insights.

