Related Experiment Video
Updated: Jan 9, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
Published on: February 25, 2022
4D Flow Cardiovascular Magnetic Resonance Uncovers the Hemodynamic Clue in Aortic Dissection
Pablo E Tobías-Castillo1, Filipa Xavier Valente2, Gisela Teixidó-Turà2
1Department of Cardiology, Vall d'Hebron University Hospital, Barcelona, Spain.
Background:
Persistent or recurrent aortic coarctation after surgical repair can create hemodynamic stress that predisposes to aneurysm formation and dissection.
Case Summary:
A 58-year-old man with prior extra-anatomic bypass repair of coarctation presented with acute interscapular pain and an upper-to-lower limb pressure gradient of >40 mm Hg. Computed tomography showed a thrombosed graft, a descending thoracic aortic aneurysm, and a Stanford type B dissection. Multimodal imaging, including 4D flow cardiovascular magnetic resonance, showed a high-velocity jet traversing the coarctation and striking the descending thoracic aorta where aneurysmal enlargement, focal wall shear stress (WSS) elevation, and the intimal tear colocalized. Hybrid repair with a frozen elephant trunk and thoracic endovascular aortic repair was performed; a subsequent type II endoleak was successfully treated by coil embolization.
Discussion:
This case highlights flow-mediated mechanisms of aneurysm expansion and dissection, and suggests that parameters such as WSS may serve as adjunctive tools to predict complications in selected patients.
Take-Home Messages:
In adults with repaired aortic coarctation, persistent or resistant hypertension should prompt evaluation for recurrent obstruction. 4D flow cardiovascular magnetic resonance can quantify WSS and abnormal flow patterns, offering mechanistic insight and potential value for risk stratification in complex aortic disease.
More Related Videos
07:12Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
Published on: September 8, 2023
11:13Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Magnetic Resonance Imaging
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Blood Flow