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Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
Published on: March 17, 2023
When Everything Else Fails: TricValve® in a Dialysis-Dependent Patient with Advanced Right Heart Failure
Aristi Boulmpou1, Alexandros Kallifatidis2, Panagiotis Charalampidis2
1St. Luke's Hospital, Panorama, Thessaloniki, Greece;Third Department of Cardiology, Aristotle University of Thessaloniki, Ippokrateio General Hospital, Thessaloniki, Greece.
Percutaneous caval valve implantation using the TricValve® system successfully treated severe tricuspid regurgitation in a dialysis-dependent patient. This minimally invasive approach stabilized hemodynamics and improved recovery in a high-risk individual.
Area of Science:
- Cardiology
- Interventional Cardiology
- Nephrology
Background:
- End-stage renal disease (ESRD) patients on dialysis often have complex cardiovascular conditions.
- Severe tricuspid regurgitation (TR) significantly impacts right heart function and can complicate management in ESRD patients.
- High-risk ESRD patients with severe TR face limited treatment options due to prohibitive surgical risks.
Purpose of the Study:
- To report the first European case of TricValve® system implantation in a dialysis-dependent patient with severe TR.
- To evaluate the feasibility and therapeutic value of percutaneous caval valve implantation in a high-risk ESRD patient.
Main Methods:
- A 72-year-old male ESRD patient with severe TR, hypotension, and cardiogenic shock underwent urgent percutaneous caval valve implantation with the TricValve® system.
- Transcatheter edge-to-edge repair was considered unsuitable due to extensive annular dilation.
Main Results:
- The TricValve® procedure was technically successful, achieving immediate hemodynamic stabilization.
- The patient experienced improved tolerance of renal replacement therapy and rapid clinical recovery.
- Follow-up imaging confirmed optimal device placement without complications.
Conclusions:
- Percutaneous caval valve implantation with the TricValve® system is a feasible and effective treatment for carefully selected, high-risk dialysis-dependent patients with severe TR.
- This minimally invasive approach offers a therapeutic alternative when traditional surgical or transcatheter options are not viable.
Related Concept Videos
Mitral Regurgitation I: Introduction
Cardiac Catheterization II: Right Heart Catheterization
Heart Failure VI: Adjunct Therapies
Hemodialysis II: Procedure and Complications
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure Drugs: Diuretics

