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Physiological Postnatal Weight Loss Nomograms in Exclusively Breastfed Healthy Infants (≥36 Weeks) during Initial

Ramandeep Kaur1, Neeraj Gupta2, Bharti Yadav3

  • 1Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, India.

Neonatology
|December 5, 2025
PubMed

Insights

New nomograms track infant weight loss in arid regions. These charts help identify excessive weight loss in exclusively breastfed newborns, crucial for preventing dehydration and illness.

Area of Science:

  • Neonatal care
  • Pediatric endocrinology
  • Infant health

Background:

  • Excessive postnatal weight loss in infants can lead to dehydration and other health issues.
  • Existing weight loss nomograms may not be accurate for arid regions due to environmental influences.
  • Developing region-specific standards is essential for accurate infant monitoring.

Purpose of the Study:

  • To create hour-specific percentile nomograms for postnatal weight loss in healthy, exclusively breastfed infants (≥36 weeks) from an arid region.
  • To facilitate early identification of infants at risk of excessive weight loss.
  • To provide a tool for clinicians in arid environments.

Main Methods:

  • A prospective cohort study involving 1730 infants in Western India.
  • Infants were weighed twice daily until 100 hours post-birth or discharge.
  • Quantile regression analysis was used to generate percentile curves for weight loss.

Main Results:

  • Median weight loss was 7.4% for vaginal births and 8.7% for cesarean births.
  • ≥10% weight loss occurred in 9.4% (vaginal) and 22.4% (cesarean) of infants.
  • The study revealed greater early weight loss but faster recovery after 48 hours compared to existing nomograms.

Conclusions:

  • The developed nomograms offer region-specific reference standards for monitoring postnatal weight loss in arid settings.
  • These standards aid in the early detection of excessive weight loss in exclusively breastfed infants.
  • The findings provide a foundation for validating similar nomograms in other arid regions globally.
Abstract

Keywords:
Cesarean birthsExclusive breastfeedingNewborn weight lossNomogramsVaginal births

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