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Incorporating Implementation Science Into Frailty Interventions for Cardiovascular Disease
Kang Hui Teow1, Jie Jun Wong1, Yang Zhao2
1Department of Cardiology, National Heart Centre Singapore, Singapore.
JACC. Advances
|December 5, 2025
Summary
Implementation science is key to addressing frailty in cardiovascular disease patients. Integrating frailty interventions into routine care requires understanding implementation barriers and facilitators within clinical trials.
Area of Science:
- Cardiology
- Implementation Science
- Geriatrics
Background:
- Frailty is prevalent in cardiovascular disease (CVD) patients.
- Frailty is associated with poor health outcomes in CVD.
Purpose of the Study:
- To highlight the role of implementation science in managing frailty in CVD.
- To advocate for integrating implementation research into CVD trials.
- To improve the adoption and routine use of frailty interventions.
Main Methods:
- Analysis of barriers and facilitators to implementation.
- Exploration of conceptual frameworks for guiding implementation.
- Suggestions for trial designs that support long-term implementation.
Main Results:
- Implementation science offers strategies to overcome challenges in frailty care.
- Conceptual frameworks aid in structuring and evaluating implementation efforts.
- Specific trial designs can enhance the sustainability of frailty interventions.
Conclusions:
- Integrating implementation science into CVD research is crucial for effective frailty management.
- Understanding implementation factors is essential for translating research into practice.
- Future CVD trials should incorporate implementation strategies to ensure lasting impact.
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