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Motion-Informed Deep Learning for Human Brain Magnetic Resonance Image Reconstruction Framework
Zhifeng Chen1,2,3, Kamlesh Pawar1, Kh Tohidul Islam1
1Monash Biomedical Imaging, Monash University, Clayton, Victoria, Australia.
NMR in Biomedicine
|December 5, 2025
Summary
This study introduces a novel deep learning method to simultaneously accelerate magnetic resonance imaging (MRI) and correct motion artifacts. The "motion-informed" deep learning model improves image quality in scans with patient movement.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Biomedical Engineering
Background:
- Motion artifacts affect approximately 30% of clinical MRI scans, degrading image quality.
- Current deep learning models address image reconstruction and motion correction separately.
- Existing methods fail to explicitly model patient motion within deep learning reconstruction frameworks.
Purpose of the Study:
- To develop a novel deep learning method for simultaneous MRI acceleration and motion artifact correction.
- To integrate motion detection and correction directly into the deep learning reconstruction process.
- To create a "motion-informed" deep learning model for enhanced MRI data acquisition.
Main Methods:
- A novel deep learning architecture was developed, integrating a motion module as an auxiliary layer.
- The model was trained to be "motion-informed," enabling it to learn and correct for motion during reconstruction.
- Image reconstruction was performed using undersampled k-space data with the trained motion-informed deep learning model.
Main Results:
- The proposed motion-informed deep learning network demonstrated superior performance compared to conventional reconstruction methods.
- Experimental results confirmed the network's effectiveness in reconstructing high-quality MRI data from motion-degraded datasets.
- The method successfully addressed undersampling artifacts alongside motion-induced artifacts like blurring, ghosting, and ringing.
Conclusions:
- The developed motion-informed deep learning approach effectively corrects motion artifacts during MRI reconstruction.
- This integrated method offers a promising solution for accelerating MRI scans while maintaining high image quality.
- The findings suggest a new paradigm for deep learning-based MRI reconstruction that accounts for patient motion.

