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Updated: Jan 9, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
Published on: November 5, 2016
Recognition and separation of Gram-positive and Gram-negative bacteria using polythiophene derivatives with
Hibiki Ogura1, Rui Kuroda1, Nobuyuki Kanzawa1
1Department of Materials and Life Sciences, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan. y-tabuch@sophia.ac.jp.
Abstract:
Water-soluble poly[3-(4-trimethylphosphinobutyl)thiophene bromide] (PTB), which has a phosphonium group at the end of its side chain and selectively recognizes and separates Gram-positive bacteria, was synthesized. Modifying its terminal group with an ethyl substitution greatly altered the bacterial response, notably causing abnormal fibrosis in Gram-negative E. coli.
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