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Updated: Jan 9, 2026

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions
Published on: June 14, 2016
Additive fabrication for NMR probe builders
Jose L Uribe1, Annie V McAllister1, Rachel W Martin2
1Department of Chemistry, University of California, Irvine 92697-2025, United States of America.
None:
Three-dimensional (3D) printing has emerged as a transformative technology for nuclear magnetic resonance (NMR) instrumentation, offering flexibility in the design and fabrication of custom tools that enhance experimental capabilities. Additive manufacturing has made it possible for many NMR labs to build their own magic angle spinning assemblies, sample handling devices, and other critical components. We summarize common 3D printing techniques, such as fused deposition modeling (FDM) and stereolithography (SLA) for polymers, along with metal printing methods like selective laser melting. By facilitating rapid prototyping, 3D printing accelerates the development and optimization of NMR systems, as well as bypassing traditional manufacturing constraints. This review also discusses perspectives on the future of 3D printing in NMR and related methods, providing cost-effective, in-house solutions that increase participation, allow for sharing and remixing of innovations, and broaden applications across chemical, biological, and materials research.
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