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Artificial intelligence in healthcare research: Research ethics perspective
Cong Ying Hey1, Spoorthy Kulkarni1,2
1Department of Clinical Pharmacology and Therapeutics, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
British Journal of Clinical Pharmacology
|December 8, 2025
Summary
Artificial intelligence (AI) in healthcare research presents complex ethical challenges. Addressing AI
Area of Science:
- Healthcare Ethics
- Artificial Intelligence Research
- Biotechnology Governance
Background:
- Current policies struggle to keep pace with rapid artificial intelligence (AI) development in healthcare.
- AI applications introduce novel ethical and legal dilemmas beyond traditional bioethics and legislation.
- Establishing definitive professional guidelines and regulations for AI in healthcare is a slow process.
Purpose of the Study:
- To examine the ethical challenges at the intersection of AI and healthcare research.
- To identify key ethical principles for responsible AI implementation in healthcare.
- To discuss ethical considerations throughout the AI development lifecycle.
Main Methods:
- Literature review of AI in healthcare ethics.
- Analysis of ethical principles relevant to AI.
- Examination of AI development lifecycle stages for ethical implications.
Main Results:
- Key ethical principles include justice, data stewardship, explainability, accountability, and sustainability.
- Ethical considerations span from AI problem identification to post-deployment evaluation.
- The dynamic nature of AI necessitates adaptive ethical frameworks.
Conclusions:
- Responsible AI in healthcare requires a proactive approach to ethical challenges.
- Adherence to core ethical principles is crucial for trustworthy AI systems.
- Ongoing dialogue and adaptive governance are essential for navigating AI's ethical landscape in healthcare.
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