Related Experiment Video
Updated: Jan 9, 2026

05:00
Using a Chemical Biopsy for Graft Quality Assessment
Published on: June 17, 2020
5.6K
Quality metrics in solid organ donation: A narrative review.
Chiara Lazzeri1, Michela Maielli2, Federico Gelli2
1Department of Emergency, Extracorporeal Membrane Oxygenation Center, Regional Transplant Center, Florence 50134, Italy. lazzeri.ch@gmail.com.
World Journal of Transplantation
|December 8, 2025
Summary
Quality metrics for organ donation are inconsistent globally. Implementing quality indicators in Poland and Italy improved donation and transplant rates, highlighting their importance for national and hospital-level interventions.
Area of Science:
- Medical Science
- Public Health
- Healthcare Management
Background:
- Evidence on quality indicators for organ donation and transplantation is heterogeneous, potentially due to variations in healthcare systems and limited data.
- Organ procurement organizations (OPOs) in the US use multiple quality metrics, including population characteristics, to assess performance.
- Quality improvement programs are established in Europe, but their impact on organ donation and transplantation outcomes requires further investigation.
Purpose of the Study:
- To review and synthesize available evidence on quality metrics for solid organ procurement in the United States and Europe.
- To identify the role and impact of quality indicators in assessing and improving organ donation and transplantation performance.
- To highlight the significance of quality assessment methods for national and hospital-level interventions.
Main Methods:
- A PubMed search was conducted to identify relevant studies on quality metrics in organ procurement.
- Evidence was summarized and analyzed by country, acknowledging differences in donation and transplantation systems.
- The review focused on quality assessment practices in the US and quality improvement programs in Europe.
Main Results:
- US Organ Procurement Organizations (OPOs) utilize a range of quality metrics, considering donor and recipient population characteristics.
- In Poland, hospitals implementing quality indicators and improvement procedures showed better outcomes than those without.
- In Tuscany, Italy, a monitoring approach based on indicators increased transplant and donation activity, particularly for controlled donation after circulatory death (cDCD) donors.
Conclusions:
- Developing robust methods for quality assessment and improvement is crucial for organ donation and transplantation authorities.
- Quality indicators play a vital role in identifying key interventions at both national and hospital levels.
- Standardized quality metrics can help optimize organ procurement processes and enhance transplant outcomes globally.
Related Concept Videos
Kidney Transplant I: Introduction
310
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
310
Kidney Transplant II: Surgical Procedure
289
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
289
Tissue Transplantation
870
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
870
Bone Marrow Sampling and Transplants
829
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
829

