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Clinical Outcomes and Complications Following Subtotal Cholecystectomy: A Single-Centre Cohort Analysis
Oday Al-Asadi1, Joussi Ramzi2, Mostafa Mahran3,4
1General Surgery, Homerton University Hospital, London, GBR.
Cureus
|December 8, 2025
Summary
Subtotal cholecystectomy (STC) is a safe option for difficult gallbladders, reducing common bile duct (CBD) injury risk. While effective, bile leaks remain a concern, necessitating standardized techniques and careful patient selection for optimal outcomes.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Biliary Surgery
Background:
- Subtotal cholecystectomy (STC) is gaining traction for managing challenging gallbladders, aiming to minimize common bile duct (CBD) injury.
- Current STC techniques and outcomes show institutional variability, with limited standardized reporting.
Purpose of the Study:
- To assess peri-operative and post-operative outcomes of STC at a tertiary center.
- To identify pre-operative factors predicting the need for STC, including prior gallstone admissions and specific imaging markers.
Main Methods:
- Retrospective cohort study of 39 patients undergoing STC (Jan 2021-Jan 2024).
- Data collected included demographics, indications, operative techniques (fenestrating vs. reconstituting), intra-operative findings, and complications.
- Primary endpoint: clinically significant bile leak; secondary endpoints: reoperation, ERCP, readmission, and mortality.
Main Results:
- Laparoscopic STC was performed in 97% of cases.
- Clinically significant bile leak occurred in 2.6% of patients; no reoperations, readmissions, or mortality were recorded.
- One patient (2.6%) required endoscopic retrograde cholangiopancreatography (ERCP).
Conclusions:
- STC provides a safe alternative to total cholecystectomy for complex gallbladder cases.
- Bile leak is a notable morbidity associated with STC.
- Operative technique and intra-operative findings impact outcomes, underscoring the need for standardization and careful case selection.
Keywords:
bile leakcholecystectomy outcomesdifficult gallbladderlaparoscopic surgerysubtotal cholecystectomy
