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The Role of Double J Stenting in Nonobstructive Acute Pyelonephritis With Acute Kidney Injury
Raniya Palliyedath1, Ram Prabahar M2, Jayanivash Jayam2
1Internal Medicine, SIMS Hospitals, Chennai, IND.
Cureus
|December 8, 2025
Summary
Double J (DJ) stenting may improve kidney recovery in acute kidney injury (AKI) patients with nonobstructive acute pyelonephritis (NO-APN). This minimally invasive procedure showed benefits in severe (Stage III) AKI cases when combined with antibiotics.
Area of Science:
- Nephrology
- Urology
- Infectious Diseases
Background:
- Nonobstructive acute pyelonephritis (NO-APN) can lead to acute kidney injury (AKI), altering clinical presentation and renal outcomes.
- Parenteral antibiotics are standard for NO-APN, but the role of minimally invasive urologic procedures remains unclear.
Purpose of the Study:
- To evaluate the effectiveness of double J (DJ) stenting in patients with NO-APN and AKI.
- To assess DJ stenting's impact on renal recovery, focusing on creatinine and inflammatory markers.
Main Methods:
- Retrospective study comparing conservative management (Group A) versus DJ stenting (Group B) in NO-APN patients with AKI.
- Outcomes assessed included renal recovery, sepsis resolution, and hospital stay duration.
- Subgroup analysis focused on Kidney Disease: Improving Global Outcomes (KDIGO) Stage III AKI patients.
Main Results:
- No significant difference in overall renal outcomes between conservative and DJ stenting groups.
- DJ stenting (Group B) showed improved outcomes in Stage III AKI patients compared to conservative management (Group A).
- Statistically significant reductions in total leukocyte count and serum creatinine were observed in Group B's Stage III AKI subgroup.
Conclusions:
- DJ stenting is a potential minimally invasive adjunct to intravenous antibiotics for NO-APN with Stage III AKI.
- The procedure may aid in promoting renal recovery in severe cases of NO-APN with AKI.
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