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Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
Published on: August 22, 2025
Safety considerations for patients using cannabis
1(Corresponding author) Professor of Pharmacy Practice; Director of Interprofessional Development; Director of Curriculum, Northeast Ohio Medical University, Rootstown, Ohio, sdugan@neomed.edu.
Cannabis use may affect mood, increase suicidal thoughts, and impact the cardiovascular system. Healthcare professionals must be aware of these potential risks in patients using cannabis.
Area of Science:
- Pharmacology and Toxicology
- Cardiovascular Medicine
- Mental Health
Background:
- Cannabis is a widely used substance with incompletely understood effects.
- Increasing legalization necessitates awareness of potential health risks.
- Limited knowledge exists regarding cannabis's full safety profile and non-psychoactive effects.
Purpose of the Study:
- To explore the association between cannabis use and mood symptoms.
- To investigate the link between cannabis use and suicidal ideation.
- To describe potential cardiovascular effects and drug interactions associated with cannabis.
Main Methods:
- Literature review and synthesis of existing research on cannabis pharmacology.
- Analysis of studies examining mental health outcomes in cannabis users.
- Examination of evidence regarding cardiovascular effects and drug interactions.
Main Results:
- Cannabis use is linked to alterations in mood and increased suicidal ideation.
- Cardiovascular effects, including potential arrhythmias and blood pressure changes, are observed.
- Interactions between cannabis and other medications are a concern.
Conclusions:
- Healthcare providers need to be informed about the multifaceted risks of cannabis use.
- Further research is crucial to fully elucidate the safety profile of cannabinoids.
- Understanding these risks is essential for patient care in the context of widespread cannabis availability.
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