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Related Experiment Video

Updated: Jan 9, 2026

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

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Predicting Post-Traumatic Epilepsy with Automated Contusion Measurements using Acute CT Images: A Competing Risk

B Berke Ayvaz, Justin R Wheelock, Daniel S Jin

Medrxiv : the Preprint Server for Health Sciences

|December 8, 2025

Summary

This summary is machine-generated.

Contusion volume and location on CT scans can predict post-traumatic epilepsy (PTE) in TBI patients. Specific frontal and temporal contusions are linked to PTE and mortality risk.

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Last Updated: Jan 9, 2026

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Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images

Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images

Published on: April 13, 2013

Area of Science:

Neuroimaging
Neurology
Medical Image Analysis

Background:

Traumatic brain injury (TBI) is a leading cause of death and disability.
Post-traumatic epilepsy (PTE) is a common complication following TBI.
Predicting PTE risk is crucial for patient management and treatment.

Purpose of the Study:

To evaluate contusion volume and location as predictors of PTE.
To consider mortality as a competing risk in TBI patients.
To utilize automated segmentation of acute CT images for analysis.

Main Methods:

Adult TBI patients were categorized into PTE, mortality, or event-free groups.
CT scans were segmented using the BLAST-CT algorithm for various hemorrhage and edema types.
Multivariable Cox models and sparse canonical correlation analysis were employed.

Main Results:

Total contusion volumes independently predicted both PTE and mortality.
Frontal and temporal contusions independently predicted PTE, while frontal contusions also predicted mortality.
Frontotemporal and insular contusions were associated with PTE but not mortality.

Conclusions:

Automated contusion segmentation from acute CT imaging can aid in predicting PTE.
Contusion volume is associated with both PTE and mortality risk.
Specific contusion locations may improve PTE risk assessment in TBI patients.