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99m Tc-RBC SPECT/CT Scintigraphy for Diagnosis of Small Intestinal Angiosarcoma : A Case Report

Yangting Mao1, Mo Wang1, Jianan Zhang1

  • 1Department of Nuclear Medicine.

Clinical Nuclear Medicine
|December 8, 2025
PubMed

A 64-year-old man presented with severe anemia (hemoglobin 56 g/L; RBC 2.60×10 12 /L) on a background of hypertension, diabetes, coronary heart disease, and cerebral thrombosis. Contrast-enhanced abdominal CT and initial endoscopy were unremarkable. Initial 99m Tc-RBC SPECT/CT scintigraphy localized active bleeding to the descending colon. However, repeat endoscopy revealed brown stool in the terminal ileum. Subsequent 99m Tc-RBC SPECT/CT scintigraphy identified a small-bowel soft-tissue mass whose position shifted confirmed epithelioid angiosarcoma of the small intestine. This case highlights the utility of 99m Tc-RBC SPECT/CT in diagnosing challenging small intestinal angiosarcoma.

Keywords:
SPECT/CTgastrointestinal bleedingsmall intestinal angiosarcoma

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