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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Sleep Bruxism: Mapping Potential Direct and Indirect Risk Pathways in EPISONO Adult Population-Based Study.

Eduardo Machado1, Jessica Klöckner Knorst2, Milton Maluly Filho1

  • 1Department of Psychobiology, Universidade Federal de Sao Paulo, São Paulo, Brazil.

Journal of Oral Rehabilitation
|December 8, 2025
PubMed
Summary
This summary is machine-generated.

Sleep bruxism (SB) is influenced by various factors. Insomnia and younger age directly predict SB, while psychological issues indirectly impact it through insomnia, affecting overall sleep health.

Keywords:
adultscomorbiditiesobservational studypathway analysissleepsleep bruxismsleep disorders

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Area of Science:

  • Sleep Medicine
  • Epidemiology
  • Psychology

Background:

  • Sleep bruxism (SB) is a common sleep-related movement disorder.
  • Understanding the multifactorial influences on SB is crucial for effective management.

Purpose of the Study:

  • To investigate the direct and indirect pathways linking sociodemographic, psychological, behavioral, and clinical factors to sleep bruxism (SB).

Main Methods:

  • Cross-sectional study of 686 adults from the Sao Paulo Epidemiological Sleep Study (EPISONO).
  • Sleep bruxism assessed via self-report, polysomnography (PSG), and combined methods.
  • Structural Equation Modelling used to analyze risk factor pathways.

Main Results:

  • Prevalence: 17.1% self-reported SB, 30.5% PSG-based SB, 7.4% combined.
  • Direct associations: SB linked to insomnia and younger age. Higher socioeconomic status correlated with self-reported SB.
  • PSG-based SB associated with obstructive sleep apnea and smoking. Anxiety and depression indirectly impacted SB via insomnia.

Conclusions:

  • Distinct pathways influence sleep bruxism (SB), with insomnia and younger age being consistent predictors.
  • Psychological factors, such as anxiety and depression, indirectly affect SB through increased insomnia.
  • Demographic, behavioral, and clinical factors show direct associations with SB, varying by assessment method.