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Chronic Hepatitis B Infection: Patient Guidance
Lung-Yi Mak1, Jimmy Che-To Lai2, Ken Liu3
1Department of Medicine, School of Clinical Medicine, The Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Insights
Chronic hepatitis B (CHB) affects millions globally, often undiagnosed. Early assessment and management, including lifestyle changes and available treatments, are crucial for preventing liver damage and cancer.
Area of Science:
- Hepatology
- Public Health
- Patient Education
Background:
- Chronic hepatitis B (CHB) is a major global cause of cirrhosis and liver cancer.
- Awareness of CHB infection is low, with less than 20% of infected individuals knowing their status.
- Many infected individuals do not receive adequate assessment and management for CHB.
Purpose of the Study:
- To provide patient guidance for individuals at risk of or living with chronic hepatitis B.
- To summarize updated knowledge on CHB assessment, management, and treatment.
- To empower patients with CHB to actively participate in their healthcare.
Main Methods:
- Development of a patient guidance document through collaboration with clinicians, scientists, patients, and patient representatives.
- Summarization of current scientific knowledge and clinical recommendations for CHB.
- Inclusion of essential measures for CHB management and prevention of transmission.
Main Results:
- Highlights the availability of safe and effective treatments for CHB in many regions.
- Recommends essential measures including lifestyle adjustments, coinfection screening, comorbidity management, fibrosis assessment, HBV transmission prevention, and liver cancer surveillance.
- Notes recent advancements in CHB treatment paradigms and new drug development.
Conclusions:
- Increased patient understanding of CHB can lead to more active participation in disease management.
- Timely assessment and management are vital for individuals with CHB to prevent complications like cirrhosis and hepatocellular carcinoma.
- This guidance aims to inform and empower individuals affected by chronic hepatitis B.
Abstract:
This patient guidance document is intended for all people at risk of or living with chronic hepatitis B (CHB) infection. Globally, CHB is one of the leading causes of cirrhosis and hepatocellular carcinoma, the most common form of liver cancer. However, less than one in five infected individuals is aware of their condition and only a small fraction of these individuals receive proper assessment and management. Safe and effective treatment is available in many countries and regions and is recommended for infected individuals who have evidence of liver damage or are at risk of complications. Several essential measures are advised for all people living with CHB, including lifestyle habits, screening for coinfection, managing comorbidities, fibrosis assessment, preventing HBV transmission, and surveillance for liver cancer. There are also recent shifts in the treatment paradigm and novel drug development. In those living with CHB, a better understanding of the disease can empower them to play an active role in management in partnership with their physicians. This guidance document has been developed in collaboration with clinicians, scientists, patients, and patient representatives to summarize updated salient knowledge to inform people at risk of or living with CHB.
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