[Auditory dysfunction in Parkinson's disease].

Area of Science:

• Neuroscience
• Otolaryngology
• Neurology

Background:

• Parkinson's disease (PD) presents with motor and non-motor symptoms impacting quality of life.
• Auditory dysfunction is an under-recognized non-motor symptom in PD, often overlooked or misinterpreted.
• Auditory changes in PD stem from aging, neurotransmitter imbalances, and neural degeneration.

Purpose of the Study:

• To review clinical manifestations and pathophysiological mechanisms of auditory dysfunction in PD.
• To discuss diagnostic approaches for auditory disorders in Parkinson's disease.
• To highlight neuroimaging findings associated with auditory dysfunction and cognitive decline in PD.

Main Methods:

• Review of existing clinical data and research on auditory dysfunction in PD.
• Analysis of neuroimaging techniques including functional MRI, MRI morphometry, and tractography.
• Correlation of auditory impairments with cognitive functions and dementia in PD patients.

Main Results:

• Auditory abnormalities occur at peripheral, brainstem, and cortical levels in PD.
• Neuroimaging reveals changes in auditory processing regions, linked to cognitive impairment.
• Auditory dysfunction in PD is multifactorial, involving aging and neurodegenerative processes.

Conclusions:

• Comprehensive assessment of auditory function is vital for PD patients.
• Developing strategies to improve auditory function in PD is necessary.
• Auditory dysfunction is a significant non-motor symptom requiring clinical attention in Parkinson's disease management.