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Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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[Christmas article: Alcohol induced rhinitis].

Anne-Sophie Homøe1, Martin Heegaard2, Lærke Ragborg2

  • 1Afdeling for Øre-, Næse- og Halskirurgi og Audiologi, Københavns Universitetshospital - Rigshospitalet.

Ugeskrift for Laeger
|December 9, 2025
PubMed
Summary
This summary is machine-generated.

Festive alcohol consumption, particularly beer, may cause nasal congestion, mimicking winter sniffles. This study suggests some holiday congestion might be alcohol-related, not viral infections.

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Area of Science:

  • Otorhinolaryngology
  • Clinical Medicine
  • Alcohol Research

Background:

  • December in Denmark is associated with increased upper respiratory symptoms.
  • The prevalence of these symptoms overlaps with festive "julefrokost" (Christmas lunch) events.
  • This overlap suggests a potential link between alcohol intake and nasal congestion.

Purpose of the Study:

  • To investigate if festive alcohol consumption, specifically beer and wine, contributes to nasal congestion.
  • To differentiate alcohol-induced nasal symptoms from common winter "sniffles".

Main Methods:

  • Randomized controlled trial involving 23 PhD students consuming either beer or wine.
  • Assessment of subjective symptom scores including Nasal Congestion Score (NCS) and Sino-Nasal-Outcome-Test-22 (SNOT-22).
  • Objective measures included fiberoptic endoscopy and olfactory function tests (Sniffin' Sticks 16) at baseline, 20 minutes, and 24 hours post-intake.

Main Results:

  • 75% of beer drinkers reported nasal congestion versus 45% of wine drinkers post-intake (p=0.083).
  • Mucosal edema increased significantly post-alcohol consumption.
  • SNOT-22 scores showed slight improvement, attributed to mood enhancement rather than sinonasal improvement. No significant changes in olfactory function were noted.

Conclusions:

  • Beer may induce transient nasal congestion more than wine, though not statistically significant.
  • Findings support the hypothesis that alcohol intake can cause "Christmas sniffles".
  • Further research is warranted to confirm the link between alcohol and sinonasal symptoms.