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Headache After Stroke: An Update for the Clinician
James Jh Im1,2, William S Kingston3,4
1Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Current Neurology and Neuroscience Reports
|December 9, 2025
Summary
Headache after stroke is common and impacts recovery. Current management is limited, but emerging procedural therapies show promise, with ongoing trials for effective treatments.
Area of Science:
- Neurology
- Stroke Medicine
- Headache Disorders
Background:
- Headache is a frequent complication of stroke, contributing to significant patient morbidity.
- Understanding post-stroke headache is crucial for improving patient outcomes in acute and outpatient care.
Purpose of the Study:
- To review current research on the incidence, pathophysiology, and management of headaches secondary to ischemic and hemorrhagic stroke.
- To synthesize findings on risk factors and therapeutic strategies for post-stroke headaches.
Main Methods:
- Literature review of recent studies on post-stroke headache.
- Analysis of research on incidence, risk factors, pathophysiology, and management strategies.
Main Results:
- Post-stroke headache is prevalent, affecting recovery and quality of life.
- Pathophysiology remains unclear with no established consensus.
- Management options are limited, with procedural therapies like ganglion blocks showing potential efficacy in ongoing trials.
Conclusions:
- Headache is a significant issue following both ischemic and hemorrhagic stroke.
- Limited evidence exists for current treatments, necessitating further research.
- Ongoing clinical trials, particularly for procedural interventions, offer hope for improved management strategies.
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