Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dissection of spatial hypoxic and inflammatory ecosystem in glioblastoma.

Cancer letters·2026
Same author

A deep learning and generative modeling pipeline for mining and engineering alkaline-stsable xylanases.

Bioresource technology·2026
Same author

Sex differences in activations to the sight of faces, scenes, body parts and tools in visual and non-visual cortical regions leading to the human hippocampus.

Biology of sex differences·2026
Same author

A multi-centre, prospective trial of a methylation-based liquid biopsy for early detection of liver cancer in high-risk populations.

Clinical and translational medicine·2026
Same author

Cudratricusxanthone A Exhibits Antitumor Activities Against NSCLC Harboring EGFR L792H and G796R Triple Mutations via Regulating EGFR-ERK/AKT/STAT3 Signaling.

Molecules (Basel, Switzerland)·2026
Same author

Affective responses during low-volume high-intensity interval exercise in overweight and obese adults: A systematic review.

Sports medicine and health science·2026
Same journal

Ti/Sr Gradient Doping with SrTiO<sub>3</sub> Coating for Mitigating Strain and Oxygen Loss in Ni-Rich Cathode.

ACS applied materials & interfaces·2026
Same journal

Metallic Lead to Perfect Perovskite: A Bottom-Up Vapor-Assisted Colloidal Strategy for High-Performance Solar Cells.

ACS applied materials & interfaces·2026
Same journal

Two-Dimensional VSe<sub>2</sub>@Polypyrrole Heterostructure Enables Stable High-Rate Lithium-Sulfur Batteries.

ACS applied materials & interfaces·2026
Same journal

A Multifunctional Hydrogel Integrating Hemostatic, Antioxidant, and Antibacterial Properties for Infected and Diabetic Wound Regeneration.

ACS applied materials & interfaces·2026
Same journal

Tunable Interfacial to Filamentary Resistive Switching Mechanism in Room-Temperature-Grown Amorphous YBa<sub>2</sub>Cu<sub>3</sub>O<sub><i>x</i></sub> with Excess Cu Addition.

ACS applied materials & interfaces·2026
Same journal

Bioinspired Rhombic VO<sub>2</sub> Metasurface with Low Solar Absorptance for Self-adaptive All-Weather Building Thermal Management.

ACS applied materials & interfaces·2026
See all related articles

Related Experiment Video

Updated: Jan 9, 2026

Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

9.3K

Self-Healing Electrogenic Living Hydrogels for Durable Bioelectronics.

Ruohan Zhang1, Yang Gao1, Seokheun Choi1,2

  • 1Bioelectronics & Microsystems Laboratory, Department of Electrical & Computer Engineering, State University of New York at Binghamton, Binghamton, New York 13902, United States.

ACS Applied Materials & Interfaces
|December 9, 2025
PubMed
Summary
This summary is machine-generated.

This study presents a self-healing conductive hydrogel using Bacillus subtilis spores for adaptive bioelectronics. The hydrogel repairs itself and enhances electrical conductivity through bacterial germination, enabling robust living electronics.

Keywords:
Bacterial endosporesElectrogenic bacteriaElectrogenic hydrogelsLiving ElectronicsSelf-healing

More Related Videos

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.8K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.5K

Related Experiment Videos

Last Updated: Jan 9, 2026

Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

9.3K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.8K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.5K

Area of Science:

  • Bioelectronics
  • Materials Science
  • Microbiology

Background:

  • Living conductive hydrogels offer potential for adaptive bioelectronics but often suffer from loss of electrical function after damage.
  • Existing materials lack robust self-healing and sustained electrogenic performance.

Purpose of the Study:

  • To develop a self-healing electrogenic living hydrogel with enhanced electrical functionality.
  • To integrate Bacillus subtilis spores for biological activity and conductivity restoration.
  • To demonstrate the hydrogel's application in a paper-based microbial fuel cell.

Main Methods:

  • Embedding Bacillus subtilis spores in a dual self-healing hydrogel matrix composed of PEDOT:PSS-PVA and cellulose acetate microcapsules loaded with carbon nanotubes.
  • Utilizing hydrogen-bonded networks for mechanical self-healing and microcapsule rupture for conductivity restoration.
  • Leveraging spore germination to trigger bacterial extracellular electron transfer (EET) for boosted conductivity.

Main Results:

  • The hydrogel demonstrated dual self-healing mechanisms, restoring both mechanical integrity and electrical conductivity.
  • Bacillus subtilis germination synergistically boosted conductivity and reduced internal resistance.
  • The hydrogel functioned as an anode in a paper-based microbial fuel cell, achieving a power density of 1.5 μW cm⁻² and an open-circuit voltage of 0.38 V.

Conclusions:

  • The developed living hydrogel platform offers a paradigm for self-repairing, high-performance bioelectronics.
  • The integration of mechanical resilience, conductivity restoration, and biologically triggered electroactivity enables advanced applications.
  • This technology holds significant potential for biosensing, energy harvesting, and soft bioelectronic systems.