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Updated: Jan 9, 2026

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Revisiting the Disulfiram-Like Reaction Between Alcohol and Oral Metronidazole

Ifeoluwa Orire1, Momi Sagoe1, Christina A Muzny2

  • 1From the Department of Epidemiology, Tulane University Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, LA.

Sexually Transmitted Diseases
|December 10, 2025
PubMed
Summary

Evidence suggests oral metronidazole (MTZ) may not cause a significant disulfiram-like reaction (DLR) with alcohol. Further research questions the need for strict alcohol abstinence during MTZ treatment.

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