Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electrolysis

Electrolysis

In a galvanic cell, the electrical work is done by a redox system on its surroundings as electrons produced by the spontaneous redox reactions are transferred through an external circuit. Alternatively, an external circuit does work on a redox system by imposing a voltage sufficient to drive an otherwise nonspontaneous reaction in a process known as electrolysis. For instance, recharging a battery involves the use of an external power source to drive the spontaneous (discharge) cell reaction in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Upcycling eggshell waste into sustainable and portable chiral membranes for the physical separation and electrocatalytic deracemization of enantiomers.

RSC advances·2026

Same author

Chiral-Encoded Pt-Ir Surfaces as Apparent Spin Filter for Enhanced Oxygen Reduction.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Phenanthrene-like Benzodichalcogenophenes: Synthesis, Electrochemical Behavior and Applications.

Molecules (Basel, Switzerland)·2026

Same author

Smartphone light-driven electrocatalytic polymerization of thiophenes.

Physical chemistry chemical physics : PCCP·2026

Same author

Bipolar electrochemical tweezers using pristine carbon fibers with intrinsically asymmetric features.

Nature communications·2025

Same author

Tunable stereoselectivity in a wireless electrochemical microreactor using natural chiral ionic liquids.

Green chemistry : an international journal and green chemistry resource : GC·2025

Search research articles

Related Experiment Video

Updated: Jan 9, 2026

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Published on: July 24, 2018

Unplugging Asymmetric Synthesis with a Wireless, Self-Pumping Electrochemical Reactor.

Sara Grecchi¹, Gerardo Salinas², Malinee Niamlaem¹

¹Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, 20133 Milan, Italy.

Journal of the American Chemical Society

|December 10, 2025

Summary

This summary is machine-generated.

This study introduces a novel electrochemical flow reactor that integrates pumping and asymmetric synthesis. This miniaturized, wireless device enables efficient, reagent-free chemical reactions with high yields and enantioselectivity.

More Related Videos

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1

Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1

Published on: April 16, 2018

Related Experiment Videos

Last Updated: Jan 9, 2026

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Published on: July 24, 2018

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1

Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1

Published on: April 16, 2018

Area of Science:

Electrochemistry
Materials Science
Organic Synthesis

Background:

Miniaturized reactors are crucial for efficient chemical synthesis.
Integrating multiple functions into a single device can overcome limitations in traditional setups.
Asymmetric synthesis requires precise control over stereochemistry.

Purpose of the Study:

To develop the first miniaturized, wireless electrochemical flow reactor for integrated reactant pumping and asymmetric synthesis.
To demonstrate the device's capability in performing various enantioselective transformations.
To establish a new paradigm for automated, reagent-free chemical manufacturing.

Main Methods:

Fabrication of a hollow, conductive polymer tube with a polypyrrole (Ppy) outer shell for pumping and a chiral thiophene-based oligomer inner layer for catalysis.
Utilizing an alternating current (AC) protocol for electrochemical reactions.
Testing the reactor's performance in ketone reduction, sulfide oxidation, and reductive amination.

Main Results:

Achieved near-quantitative yield (99%) and exceptional enantioselectivity (>99% ee) in acetophenone reduction.
Successfully synthesized Ugi's amine with high stereocontrol (>99.5% ee) via direct asymmetric synthesis.
Demonstrated the reactor's versatility across three distinct chemical transformations.

Conclusions:

The integrated electrochemical flow reactor overcomes mass-transport limitations and eliminates the need for external pumps.
This technology offers a reagent-free and pump-free approach to asymmetric synthesis.
The validated predictive model supports the rational design of smart, automated chemical manufacturing platforms.