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Published on: October 28, 2015
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Hybrid nanomaterials-based biomedical phototheranostic platforms.
Jing Ye1, Xiawei Dong1, Hui Jiang1
1State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory), School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, People's Republic of China.
Progress in Biomedical Engineering (Bristol, England)
|December 10, 2025
Summary
New hybrid nanomaterials offer advanced disease diagnosis and treatment by combining multiple properties. These versatile nano-platforms show significant promise for personalized medicine and improved patient outcomes in various medical applications.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- Hybrid nanomaterials possess unique surface modification or core characteristics, integrating multiple chemical, physical, and optical properties.
- These advanced materials present personalized application prospects for disease management and treatment.
- They have the potential to significantly improve the diagnosis and treatment of various diseases.
Purpose of the Study:
- To review the synthesis methods and structural characteristics of novel hybrid nanomaterials.
- To explore the application of these nanomaterials in advanced imaging technologies.
- To summarize the therapeutic effects of theranostics and other treatment modalities guided by imaging.
Main Methods:
- Review of recent literature on hybrid nanomaterial synthesis and characterization.
- Focus on metallic oxide-containing, biopolymer-containing, and in situ biosynthesized hybrid nanomaterials.
- Analysis of applications in magnetic resonance imaging, photoacoustic, fluorescence, and computed tomography imaging.
Main Results:
- Hybrid nanomaterials demonstrate significant potential in enhancing diagnostic imaging accuracy.
- Integration of imaging and therapy (theranostics) shows promise for cancer immunotherapy, photomedicine, and photothermal therapy.
- Successful application of hybrid nanomaterials as nano-platforms for combined diagnosis and treatment.
Conclusions:
- Hybrid nanomaterials offer a versatile platform for advanced biomedical imaging and therapeutic interventions.
- Further research is needed to address challenges in their clinical translation and optimize their nano-platform capabilities.
- These materials hold substantial promise for the future of personalized medicine and disease management.
