A Case Report of Acute Generalized Pustular Bacterid Preceded by Tinea Pedis

Acute generalized pustular bacterid (AGPB) is a rare dermatological condition characterized by the abrupt onset of a generalized pustular eruption, often occurring secondary to an upper respiratory tract streptococcal infection. Histopathological findings typically reveal epidermal pustules and/or leukocytoclastic vasculitis. Notably, antibiotic therapy has been shown to be effective in managing this condition. We present a rare case of AGPB elicited by tinea pedis. This report seeks to improve clinicians' competence in the accurate identification of this condition.

A 72-year-old Chinese male patient was admitted to the hospital with AGPB that developed following treatment for tinea pedis. The diagnosis was supported by clinical manifestations and a pathological biopsy. After 1 week of combination therapy with intravenous cefuroxime sodium and topical triamcinolone acetonide and econazole nitrate cream, the skin lesions showed significant improvement. The patient was discharged upon achieving stable condition.

This case highlights that for patients presenting with acute generalized pustular eruptions accompanied by tinea pedis, AGPB should be included in the differential diagnosis. Early recognition and targeted treatment can lead to a favorable prognosis.