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A Retrospective Study Revealed Potential Cross-Transmission of Hepatitis B Virus Between Great Apes and Small Monkeys
Foupouapouognigni Yacouba1, Modiyinji Abdou Fatawou2, Njouom Richard2
1Biochemistry Department, Faculty of Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Abstract:
RNA extraction from five HBsAg-positive Cercopithecidae samples, followed by semi-nested PCR of the four overlapping regions of the HBV genome and phylogenetic analyses, yielded a complete HBV genome. This strain from a Cercopithecus preussi sample has close genetic proximity to isolates from Cameroonian great apes, suggesting cross-species transmission of HBV.
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