A new method of behavioral analysis in Caenorhabditis elegans using a paintbrush for liquid samples

This study introduces a paintbrush assay for delivering liquid reagents to Caenorhabditis elegans, overcoming limitations of glass capillaries with viscous or aggregated solutions. Using sorbitol, avoidance patterns matched between methods, but the brush reduced time at high viscosity. Applied to tannic acid, avoidance increased with concentration, confirming the assay's effectiveness and applicability to diverse reagents.