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Published on: June 3, 2021
[Computer-assisted modeling of hemodynamic parameters in normal bifurcation of common carotid artery]
V P Derbilova1, R A Vinogradov1,2, Yu N Zakharov3,4
1Kuban State Medical University of Ministry of Ministry of Healthcare of the Russian Federation, 350063, Krasnodar, Russian Federation.
Insights
Computational fluid dynamics identified atherosclerosis risk zones in carotid artery bifurcations. Low wall shear stress pinpointed the proximal internal carotid artery as a key area for plaque development.
Area of Science:
- Biomedical Engineering
- Cardiovascular Research
- Medical Imaging
Background:
Computational fluid dynamics is currently widely used to study the parameters of blood flow and their alterations in pathological states and are important indicators for diagnosis of atherosclerosis.
Objective:
This study was aimed at determining risk zones for development of atherosclerosis by means of computational fluid dynamics in patients without carotid artery pathology.
Patients And Methods:
Using contrast-enhanced computed tomography, a total of 10 bifurcations of common carotid arteries were examined. The obtained findings were analyzed by means of computational fluid dynamics. The area of bifurcation was divided into segments. In each segment, we identified zones most prone to the development of atherosclerosis.
Results:
The obtained findings made it possible to draw a conclusion that in patients without pathology of carotid arteries, the zone of bifurcation is a place of potential development of atherosclerotic plaques. It was confirmed by low values of wall shear stress. Besides, our study made it possible to determine exact localization of risk zones, i. e., proximal portion of the internal carotid artery.
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