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Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
[Rotational atherectomy in the treatment of acute lower limb ischemia (clinical case reports)]
S A Papoyan1, A A Shchegolev2, A E Markarov3
1City Clinical Hospital named after F.I. Inozemtsev, 105187, Moscow, Russian Federation; N.I. Pirogov National Research Medical University, Ministry of Health of the Russian Federation, 117321, Moscow, Russian Federation; Research Institute of Healthcare Organization and Medical Management, 115184, Moscow, Russian Federation; Russian Medical Academy of Continuing Professional Education, Ministry of Health of the Russian Federation, 125445, Moscow, Russian Federation.
Despite significant advances in angiosurgery, the treatment of acute limb ischemia remains a challenging clinical problem. Historically, the mainstay of therapy consisted of open thrombectomy and bypass surgery, later supplemented by selective thrombolysis and percutaneous angioplasty techniques. However, even with these approaches, there remains a high risk of adverse outcomes, including amputations and mortality. A breakthrough in the treatment of occlusive-stenotic lesions in the femoropopliteal segment has been the advent of modern endovascular technologies. Numerous studies confirm their clinical efficacy and promise in acute ischemia. Particular importance has been given to a multidisciplinary approach combining advancements in vascular surgery, interventional radiology, and intensive care. Among innovative methods, rotational atherectomy deserves special attention as a technology demonstrating excellent results in treating acute occlusions of the femoropopliteal zone. The article presents clinical cases of successful treatment of femoral-popliteal lesions in acute ischemia of the lower extremities using rotational atherectomy devices.
Despite significant advances in angiosurgery, the treatment of acute limb ischemia remains a challenging clinical problem. Historically, the mainstay of therapy consisted of open thrombectomy and bypass surgery, later supplemented by selective thrombolysis and percutaneous angioplasty techniques. However, even with these approaches, there remains a high risk of adverse outcomes, including amputations and mortality. A breakthrough in the treatment of occlusive-stenotic lesions in the femoropopliteal segment has been the advent of modern endovascular technologies. Numerous studies confirm their clinical efficacy and promise in acute ischemia. Particular importance has been given to a multidisciplinary approach combining advancements in vascular surgery, interventional radiology, and intensive care. Among innovative methods, rotational atherectomy deserves special attention as a technology demonstrating excellent results in treating acute occlusions of the femoropopliteal zone. The article presents clinical cases of successful treatment of femoral-popliteal lesions in acute ischemia of the lower extremities using rotational atherectomy devices.
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