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Obesity and Diabetes in Mexico: An Approach to the Intestinal Microbiota
Ruth Michelle Acosta-Meneses1, Esther Ramírez-Moreno2, Laura Berenice Olvera-Rosales1
1Instituto de Ciencias Básicas e Ingeniería, Área Académica de Química, Universidad Autónoma del Estado de Hidalgo, Carr. Pachuca-Tulancingo km. 4.5, Pachuca 42184, Hidalgo, Mexico.
Nutrients
|December 11, 2025
Summary
Obesity and diabetes are rising in Mexico, linked to lifestyle, genetics, and gut microbiota changes. Restoring microbial balance shows promise for managing these metabolic disorders.
Area of Science:
- Metabolic disorders
- Microbiome research
- Epidemiology
Background:
- Obesity and diabetes prevalence is alarmingly high globally, with Mexico significantly affected.
- These metabolic disorders are multifactorial, influenced by lifestyle, genetics, and gut microbiota.
- Gut microbiota dysbiosis is implicated in insulin resistance, inflammation, and fat accumulation.
Purpose of the Study:
- To review the epidemiology of obesity and diabetes in Mexico.
- To analyze prevalence, risk factors, and the role of the intestinal microbiota.
- To explore potential microbiota-targeted interventions.
Main Methods:
- Literature review of epidemiological studies.
- Analysis of risk factors including lifestyle and genetics.
- Examination of the gut microbiota's role in metabolic regulation.
Main Results:
- Specific microbial patterns are observed in Mexican individuals with obesity and diabetes.
- Diet and microbiota composition interact uniquely, affecting metabolic health.
- Dietary modifications and probiotics show potential for improving metabolic parameters.
Conclusions:
- Gut microbiota plays a critical role in obesity and diabetes development in Mexico.
- Further research is needed for personalized, microbiota-targeted therapies.
- Integrative approaches combining nutrition and microbiome interventions are crucial for future management.
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