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Murine Fetal Echocardiography
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Heart Morphometry in Standard Second Trimester Scan.

Alexandru-Cristian Comănescu1, Dragoș-Ovidiu Alexandru2, Maria-Cristina Comănescu3

  • 1Department of Obstetrics and Gynaecology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.

Diagnostics (Basel, Switzerland)
|December 11, 2025
PubMed
Summary
This summary is machine-generated.

Detailed fetal cardiac measurements can be obtained during routine second trimester anomaly scans without increasing scan time. This approach supports early detection of fetal heart abnormalities.

Keywords:
anomaly scancardiac morphometryfetal heart

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Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Medical Imaging

Background:

  • Routine second trimester anomaly scans utilize standard cardiac views.
  • Detailed fetal cardiac morphometry is not currently standard practice.
  • The feasibility of comprehensive cardiac measurements within routine scans is unexplored.

Purpose of the Study:

  • To assess if comprehensive fetal cardiac morphometry can be acquired from standard views during routine second trimester anomaly scans.
  • To evaluate the reproducibility and impact on examination time of these measurements.
  • To compare obtained measurements with established reference ranges.

Main Methods:

  • Prospective study of 92 uncomplicated singleton pregnancies.
  • Cardiac measurements obtained using standard International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) and Society of Radiologists in Ultrasound (SRUOG) planes.
  • Evaluation of feasibility, reproducibility, and scanning time impact.

Main Results:

  • 100% success rate in obtaining all morphometric measurements.
  • Minimal, non-significant increase in mean scanning time (3.30 min, p=0.063).
  • High intra-observer reproducibility (r > 0.80 for major dimensions) and most z-scores within ±2 SD.

Conclusions:

  • Comprehensive fetal cardiac morphometry is feasible within routine second trimester anomaly scans.
  • Integration does not significantly prolong examination time.
  • This method can aid in the early identification of atypical fetal growth and cardiac remodeling.