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Related Experiment Video

Updated: Jan 9, 2026

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
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Wearable Multispectral Sensor for Newborn Jaundice Monitoring.

Fernando Crivellaro1, Ana Isabel Sousa Pedroso1, Anselmo Costa2

  • 1Department of Physics, Faculty of Science and Technology, NOVA University of Lisbon, Caparica Campus, 2829-516 Caparica, Portugal.

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|December 11, 2025
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Summary
This summary is machine-generated.

A new continuous, non-invasive device monitors newborn jaundice (high bilirubin levels) remotely. This innovation aids early detection and management of neonatal hyperbilirubinemia, improving infant health outcomes.

Keywords:
bilirubinjaundicemultispectral sensornewbornsnon-invasiveoptical sensorwearable sensors

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Area of Science:

  • Neonatal Medicine
  • Biomedical Engineering
  • Medical Device Development

Background:

  • Newborns' immature systems increase vulnerability to environmental factors.
  • Neonatal jaundice, caused by high unconjugated bilirubin, poses neurotoxic risks.
  • Current transcutaneous bilirubinometry (TcB) devices are hospital-bound, limiting continuous monitoring.

Purpose of the Study:

  • To develop a continuous, non-invasive bilirubin monitoring device for newborns.
  • To enable remote evaluation of neonatal jaundice, both in and out of hospital settings.

Main Methods:

  • A novel non-invasive device utilizing a mini-spectrometer in the visible range was developed.
  • Device calibration was performed using phantoms.
  • In vitro experiments compared the device's performance against a gold-standard bilirubinometer.

Main Results:

  • The device demonstrated a clinically acceptable deviation of 1 mg/dL compared to the gold standard.
  • Experiments explored the practical range of bilirubin variation in newborns.
  • The developed device showed potential for remote monitoring of neonatal jaundice.

Conclusions:

  • The continuous bilirubin monitoring device offers a promising solution for managing neonatal jaundice.
  • This technology facilitates remote and continuous assessment, improving accessibility and early detection of hyperbilirubinemia.
  • The device's non-invasive nature and potential for out-of-hospital use represent a significant advancement in neonatal care.