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Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.

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Fabrication and Characterization of Superconducting Resonators
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Coherent-Phase Optical Time Domain Reflectometry for Monitoring High-Temperature Superconducting Magnet Systems.

Matthew Leoschke1, William Lo1, Victor Yartsev2

  • 1Ken and Mary Alice Lindquist Department of Nuclear Engineering, The Pennsylvania State University, 205 Hallowell Building, University Park, PA 16802, USA.

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|December 11, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a fiber optic sensing technique to monitor high-temperature superconducting magnets in fusion reactors. It effectively detects thermal anomalies, crucial for preventing damaging quenches in these complex systems.

Keywords:
Rayleigh scatteringdistributed temperature sensingfusionhigh-temperature superconductorsoptical fibersquench detection

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Area of Science:

  • Materials Science
  • Superconductivity
  • Fusion Energy Engineering

Background:

  • High-temperature superconducting (HTS) magnets in fusion reactors face monitoring challenges due to time-dependent coils, inductive voltages, and radiation-induced defects.
  • These factors can lead to non-uniform critical current, manufacturing defects, and potential quench initiation, posing a risk of permanent magnet damage.
  • HTS magnets exhibit localized normal zones due to lower propagation velocity, increasing vulnerability compared to low-temperature superconductors.

Purpose of the Study:

  • To present and validate a fiber optic interrogation technique for monitoring HTS magnet systems, particularly for magnetic confinement fusion.
  • To address the need for reliable monitoring systems that can detect incipient quench events and prevent magnet damage.
  • To demonstrate the suitability of fiber optic sensors in the harsh electromagnetic environments of fusion reactors.

Main Methods:

  • Utilized coherent-phase optical time domain reflectometry (OTDR) for high-sampling-rate (tens of kHz) data acquisition.
  • Employed fiber optic sensors, which are immune to electromagnetic interference, unlike traditional voltage-based sensors.
  • Embedded fibers within HTS magnet coils for in-situ monitoring.

Main Results:

  • Successfully detected localized thermal transients at cryogenic temperatures as low as 6 K.
  • Validated the technique using fibers embedded in HTS magnet coils at 77 K.
  • Demonstrated the capability of coherent-phase OTDR to achieve necessary sampling rates for rapid quench detection over long distances.

Conclusions:

  • The presented fiber optic interrogation technique is effective for monitoring HTS magnet systems in fusion applications.
  • Coherent-phase OTDR offers a viable solution for rapid detection and mitigation of quench events in demanding environments.
  • This technology holds significant potential for ensuring the reliability and safety of future fusion reactors.