Related Experiment Video

Updated: Jan 9, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
03:08

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

Published on: October 3, 2025

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Rho/ROCK Pathway as a Therapeutic Target in Multiple Diseases

Zixiu Cheng1, Shannon Erhardt1,2, Jun Wang1,2

  • 1Department of Pediatrics, McGovern Medical School at UTHealth, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

International Journal of Drug Discovery and Pharmacology
|December 11, 2025
PubMed
Summary

The Rho/ROCK signaling pathway regulates key cellular functions. Targeting this pathway with ROCK inhibitors shows therapeutic promise for diseases like cancer and cardiovascular disorders.

Keywords:
ROCKRhodrug-targetingfibrosis

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