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Updated: Jan 9, 2026

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
High-intensity Interval Versus Moderate-intensity Continuous Training in Heart Failure Rehabilitation: A
Victor Joseph1, Derren Rampengan2, Stevanus Surya3
1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.
High-intensity interval training (HIIT) shows greater benefits than moderate-intensity continuous training (MICT) for heart failure patients. HIIT improves cardiac function, peak oxygen uptake, and functional capacity, enhancing overall patient outcomes.
Area of Science:
- Cardiology
- Exercise Physiology
- Rehabilitation Medicine
Background:
- Exercise training is recommended for heart failure (HF) management.
- Both high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) show potential benefits.
- A systematic review is needed to compare HIIT and MICT effects on key patient outcomes.
Purpose of the Study:
- To compare the efficacy of HIIT versus MICT in individuals with heart failure.
- To evaluate the impact on cardiopulmonary fitness, functional capacity, cardiac function, and quality of life (QoL).
Main Methods:
- Systematic review and meta-analysis adhering to PRISMA guidelines.
- Searched multiple databases including PubMed, CENTRAL, Scopus, and Web of Science.
- Assessed risk of bias using the Revised Cochrane Risk-Of-Bias Tool (RoB 2).
Main Results:
- Included 21 randomized controlled trials with a low risk of bias.
- HIIT significantly improved left ventricular ejection fraction (LVEF), peak oxygen uptake (peak VO2), and the six-minute walk test (6MWT).
- HIIT demonstrated non-significant trends towards improved quality of life (QoL) and oxygen pulse.
Conclusions:
- HIIT is more effective than MICT for improving functional capacity in heart failure patients.
- HIIT demonstrates superior outcomes in left ventricular ejection fraction (LVEF), peak oxygen uptake (peak VO2), and six-minute walk test (6MWT) performance.
- HIIT positively impacts cardiac functional outcomes in individuals with heart failure.
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