Related Experiment Video
Updated: Jan 9, 2026

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
Optimal exercise dose for glycemic control in prediabetes across different exercise types
Ruixiang Yan1, Yueming Li1, Shiqi Jia1
1School of Athletic Training, Guangzhou Sport University, Guangzhou, Guangdong, China.
Abstract:
This study assessed the optimal exercise modality and dose for HbA1c reduction in individuals with prediabetes, taking baseline BMI into account. We searched six databases and conducted pairwise, network, and dose-response meta-analyses. Thirty-nine RCTs (3421 participants) showed that all exercise modalities significantly reduced HbA1c compared with controls, with HIIT showing the greatest effect, followed by combined, aerobic, resistance, and mind-body training. Dose-response analysis identified an optimal dose of 850 METs·min/week, whereas the minimum effective dose varied according to BMI and exercise type. These findings indicate that exercise improves HbA1c in prediabetes through a nonlinear dose-response and support BMI-stratified, individualized exercise prescriptions to optimize glycemic control.
More Related Videos
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
08:01Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice
Published on: May 16, 2021
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Oral Hypoglycemic Agents: Biguanides and Glitazones