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Carbon Monoxide Poisoning-Induced Myositis.

Cyrine Abid1, Zouhour Gassara1, Afef Feki1

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European Journal of Case Reports in Internal Medicine
|December 11, 2025
PubMed
Summary
This summary is machine-generated.

Carbon monoxide (CO) poisoning can rarely cause myositis, a muscle inflammation. Magnetic resonance imaging (MRI) is crucial for diagnosing and monitoring this condition, alongside early hyperbaric oxygen therapy.

Keywords:
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Area of Science:

  • Neurology
  • Toxicology
  • Musculoskeletal Medicine

Background:

  • Carbon monoxide (CO) poisoning is a common yet potentially fatal condition.
  • Neurological and systemic complications are well-documented, but muscle involvement, specifically myositis, is a rare sequela.
  • This case highlights an unusual presentation of CO poisoning.

Purpose of the Study:

  • To report a rare case of myositis following carbon monoxide poisoning.
  • To emphasize the diagnostic utility of Magnetic Resonance Imaging (MRI) in identifying CO-induced myositis.
  • To underscore the importance of early recognition and treatment of CO poisoning complications.

Main Methods:

  • A case report of a 38-year-old male with CO poisoning.
  • Diagnostic workup included laboratory tests, MRI, electromyography, and X-ray.
  • Exclusion of other potential causes of myositis was performed.
  • Treatment involved intensive care, hyperbaric oxygen therapy, anti-inflammatory medications, and rest.

Main Results:

  • The patient developed persistent thigh myalgia and weakness one month post-CO exposure.
  • MRI revealed active myositis in the vastus lateralis muscle.
  • Other diagnostic tests were unremarkable, and alternative myositis causes were excluded.
  • Treatment led to symptom alleviation and lesion regression on follow-up MRI.

Conclusions:

  • Myositis is a rare but recognized complication of carbon monoxide poisoning.
  • MRI is an invaluable non-invasive tool for diagnosing CO-induced myositis and monitoring treatment response.
  • Prompt recognition and management, including hyperbaric oxygen therapy, are critical for improving outcomes in CO poisoning patients.