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A 2-year retrospective study of endodontic microsurgery for bone fenestration
Lei Zhang1, An-Na Wang1, Han Zheng2
1Department of Endodontic Dentistry, Hefei Stomatological Clinic College, Anhui Medical University and Hefei Stomatological Hospital, Hefei, China.
JPMA. the Journal of the Pakistan Medical Association
|December 11, 2025
Summary
Endodontic microsurgery effectively treats complex periapical lesions with bone fenestration. Periodontal disease and guided tissue regeneration significantly influence healing outcomes in these cases.
Area of Science:
- Endodontics
- Oral Surgery
- Periodontology
Background:
- Complex periapical lesions pose treatment challenges.
- Bone fenestration requires specialized surgical approaches.
- Endodontic microsurgery offers a minimally invasive solution.
Purpose of the Study:
- To assess the clinical effectiveness of endodontic microsurgery for bone fenestration.
- To identify prognostic factors influencing healing after endodontic microsurgery.
- To evaluate treatment outcomes in patients with complex periapical lesions.
Main Methods:
- Retrospective cohort study of 52 teeth from 42 patients undergoing endodontic microsurgery.
- Data collected on patient demographics, lesion characteristics, and treatment variables.
- Follow-up duration of at least 24 months.
- Statistical analysis using SPSS 23 to identify influencing factors.
Main Results:
- High success rate (92.3%) for endodontic microsurgery in treating bone fenestration.
- Periodontal disease and guided tissue regeneration identified as significant factors affecting healing (p<0.05).
- No significant difference in outcomes based on age or gender.
Conclusions:
- Endodontic microsurgery is a highly effective treatment for complex periapical lesions, including bone fenestration.
- Early healing of bone fenestration is significantly influenced by the presence of periodontal disease and the use of guided tissue regeneration.

