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Generation of iPSC-Derived iNKT Cells with Pro-Hematopoietic Activity

Akhilesh Kumar1, Sarah Ferguson2, Saritha S D'Souza1

  • 1Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, 53712, USA.

Stem Cell Reviews and Reports
|December 11, 2025
PubMed
Summary

Researchers reprogrammed human invariant natural killer T (iNKT) cells into induced pluripotent stem cells (iPSCs). These iNKT-iPSCs were differentiated into functional iNKT cells that promote bone marrow hematopoiesis.

Keywords:
HematopoiesisInduced pluripotent stem cellsMyeloid progenitorsReprogrammingiNKT cells

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