Related Experiment Video
Updated: Jan 8, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Precancerous Squamous Lesions of the Vulva
Kathryn C Welch1, Hope K Haefner, Natalie A Saunders
1University of Michigan, Ann Arbor, Michigan.
Abstract:
The rate of vulvar cancer rates is rising, with high-grade squamous intraepithelial lesions, also known as vulvar intraepithelial neoplasia, and differentiated vulvar intraepithelial neoplasia representing key premalignant precursors to vulvar squamous cell carcinoma. Recent advances in classification and understanding of its causes-both human papillomavirus (HPV) associated and HPV independent-have significant implications for the diagnosis and management of these conditions. This review summarizes the evolving terminology, pathogenesis, clinical presentation, and current treatment strategies for vulvar squamous precancers, emphasizing the importance of distinguishing between the two major precancer subtypes to guide appropriate care.
More Related Videos
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
External Female Genitals
Disorders of the Female Reproductive System
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Vagina
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

