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Updated: Jan 8, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valve surgery in mitral annular calcification
Martin Misfeld1,2,3,4, Tristan D Yan1,2,3
1Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia.
Insights
Mitral annular calcification (MAC) presents surgical challenges but offers various techniques for safe valve implantation. Individualized approaches ensure adequate treatment for high-risk patients with MAC.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Mitral annular calcification (MAC) is a complex pathology linked to cardiovascular risk factors and inflammatory conditions.
- MAC poses significant surgical risks, including atrioventricular dehiscence and circumflex artery injury.
Abstract:
Mitral annular calcification (MAC) remains a challenging pathology in the context of mitral valve disease. It is associated with known cardiovascular risk factors, as well as a variety of chronic inflammatory, infective, or connective tissue diseases. Surgically, patients are at specific operative risk for atrioventricular dehiscence or rupture and/or injury to the circumflex artery. To mitigate these risks, a broad portfolio of surgical options exists to safely anchor annular sutures. This can be performed after the calcium bar has been removed and the posterior annulus reconstructed with a patch, or even when the calcium bar is left in place. Knowledge of these techniques will help surgeons manage MAC and implant a properly sized valve. Even in the presence of severe MAC with additional involvement of the mitral valve leaflets, transatrial transcatheter heart valve (THV) implantation may be a viable option. An individualized decision-making process to determine the applicable technique should be used for patients with MAC, leading to adequate treatment for this high-risk patient group.
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